this article in Nature, is "the science of science ... It has its roots in the philosophy of science and the study of scientific methods" with a primary focus being the study of the reproducibility of experimental findings.
The article points out "the decline effect, an idea ... that the size of an effect decreases over repeated replications," acknowledges experimenter expectancy effects and the power of double-blinding and expects that "self-examination can only strengthen the scientific process for all."
And when we try something new in our testing, we subject that thing to testing, don't we? Don't we?